Ezra first rose to prominence in the mid-2000s for his individual blogging, before being picked up to blog for The American Prospect and then the Washington Post.
In 2014, he co-founded the news website Vox.com, where he served as Executive Director and hosted the podcast The Ezra Klein Show. While at Vox, Ezra helped start the Future Perfect vertical, which runs evidence-driven stories about a variety of topics, many of which are related to focus areas in effective altruism.
In 2020 he published the book Why We're Polarized. In January, he left Vox to start a new column and host a revamped Ezra Klein Show at the New York Times.